Results. CMV disease developed in 29 of 113 (26%) D+R- patients at a median of 185 days (interquartile range 116-231 days) post transplant, including CMVsyndrome (66%) and tissue invasive disease (34%). The incidence of CMVdisease was higher in patients who underwent re-transplantation (57% vs. 24%) and this factor was independently associated with a higher risk of CMVdisease in multivariable analysis (hazard ratio, check details 4.02; 95% confidence interval, 1.3-13; P = 0.016). Other demographic
and transplant variables were not independently associated with a risk of late-onset CMVdisease.
Conclusions. Despite a comprehensive analysis of patient and transplant variables, only re-transplantation was identified as a risk factor for CMVdisease in D+R- kidney transplant recipients who received antiviral prophylaxis, but had limited clinical predictive value. The development of novel laboratory markers to identify patients at greatest risk for CMVdisease should be a priority for future studies.”
“Purpose: To determine the prevalence and predictors of infection in diabetic patients with diabetic ketoacidosis (DKA) who were >= 18 years.
Methods: A retrospective cohort design was adopted for this study. A total of 967 diabetes ketoacidosis patients from Hospital Pulau Pinang for the 3-year period, Jan 2008 – Dec 2010, were identified and enrolled.
The data were analysed, as appropriate, by Student t-test and ANOVA for the normally distributed data, Mann-Whitney MAPK Inhibitor Library molecular weight U rank sum and Kruskall-Wallis tests for continuous, non-nominal data and Chi-square for dichotomous variables. Odd Ratios with 95% confidence Napabucasin cost interval (CI) were also presented where applicable.
Results: Of the total diabetes ketoacidosis patients, 112 (11.6 %) were cases without infection, 679 (70.2 %) bacterial infection cases and 176 (18.2 %) presumed viral infection cases. The mean white blood count (WBC) for all the patients was 18,177 +/- 9,431 while 721 (74.6 %) had leukocytosis,
defined by WBC >= 15,000/mm(3). WBC differential, leukocytosis, as well as sex and body temperature were not significant predictors (p >. 05) of bacterial infection. There was, however, a significant difference (p <. 05) in terms of age within groups, as those > 57 years showed a higher rate of infection.
Conclusion: The infection rate in elderly patients with DKA is high and a majority of them lack clinical evidence. Age has a significant effect on the rate and prediction of infection. Leukocytosis is commonly found but severe ketoacidosis was more likely than the presence of infection.”
“Cymbopogon distans (Nees ex Steud.) Wats is a perennial aromatic grass growing wild in the temperate Himalayan region. In order to find new ecological areas for its commercial cultivation, an attempt has been made to introduce this plant to the sub-tropical region.