MATERIALS AND METHODS: A total of 72 children, aged between 6 and 15 years, with ChROM were selected and randomly divided into three groups after assessment of oral mucositis (OM) by WHO grading system. Glycerine (control), E, and P were topically applied in group I, II, and III, respectively, and the prognosis of OM was assessed by functional, objective, and subjective parameters.
RESULTS: Patients of group II and III showed significant improvement when ChROM was analyzed through scoring systems – WHO grading, Oral Mucositis
Assessment Scale (OMAS), and Children’s International OICR-9429 in vivo Mucositis Evaluation Scale (ChIMES) as compared to group I (P < 0.001); however, there was no significant difference between groups II and III.
CONCLUSION: Both the drugs E and P per se are effective for treatment of OM with P being not effective for the treatment of severe mucositis (grade 4). Combination of E and P and additional agents may be tried for better results.”
“Contents Routine semen evaluation includes volume, motility, vital staining for live-dead ratio and pathomorphology including Spermac (R) staining for evaluation of the acrosome. In recent years, depending on the species, also the hypoosmotic swelling
AZ 628 (HOS) test has been applied routinely for evaluation of semen quality. In this respect, a significant correlation between the ability of spermatozoa to swell in HOS test and the fertilizing ability
has been reported. Also for evaluation of dog semen, reference has been made to the HOS test; however, its correlation to conventional semen parameters so far is discussed controversially. In the present study, the results of 400 semen examinations from stud dogs presented at our clinic were evaluated for their correlations between conventional semen parameters (motility, live/dead ratio, pathomorphology), conventional semen parameters and age, Spermac (R) staining and HOS test, respectively. Volasertib chemical structure We found a significant correlation of age and sperm concentration (p<0.01), total sperm count (p<0.0001), percentage of progressively motile sperm (p<0.01) and live spermatozoa (p=0.012). Furthermore, several correlations between conventional semen parameters were identified. Percentage of sperm with normal acrosome identified by Spermac (R) staining correlated significantly with live spermatozoa (p<0.0001) and percentage of progressively motile sperm (p<0.01). A significant correlation was proven between curled tails in HOS test and age (p<0.001), motility (p<0.0001), live sperm (p<0.0001), acrosomal status (p<0.05), pathomorphology (p<0.0001) and sperm concentration (p=0.011). These results indicate that Spermac (R) staining and the HOS test are useful in improving canine semen analysis.