e., where the planning and executing of eye movements is physically impossible. Following the findings of Ball et al. (2013), no effect of eye-abduction on visual working memory performance was expected at any stage. Experiment 1 examined the extent

to which eye-abduction disrupts memory span when applied only during the encoding stage for visual and spatial memoranda. This was accomplished by having participants encode memoranda in an eye-abducted position at the beginning of each trial, then immediately following presentation their trunk and head where rotated such that their eye was placed in a non-abducted frontal position. This was a passive manipulation in which 5-FU mw the experimenter rotated the participant’s chair while they maintained fixation, and did not require any active generation of saccadic eye movements by participants. The procedure followed that previously described by Ball et al. (2013) with

one important addition. Because the encoding manipulation required that participants head and trunk be rotated mid-way in a trial in conjunction with simultaneous counter-rotation of the eye to maintain fixation, this raised the possibility that the rotation in itself could cause disruption independent of any effect of eye-abduction. To control for this possibility we created an additional control condition in which Trametinib manufacturer participants encoded memoranda with their eyes rotated 20° to the left or right, immediately after which their head and trunk were rotated to a frontal position. Critically, while this condition still required counter-rotation of the eye and head and trunk rotation mid-way through each trial as occurred for 40° abducted trials, participants in the 20° abducted position were still able to physically move their eyes into the temporal hemifield and engage in oculomotor preparation. If the oculomotor system does contribute to the encoding of memoranda in spatial working memory, then disruption of Corsi performance should only be observed during the 40° abduction condition when memoranda

are presented in participants’ temporal hemifield. Fourteen participants took part in this experiment (5 male, mean age 20.8, SD = 3.0, 12 were right eyed). Participants Glutathione peroxidase were from Durham University and received course credit for taking part. Ethical approval was obtained from the Psychology Research Ethics Committee at Durham University, and participants gave informed consent. All participants had normal or corrected-to-normal vision. In the case of corrected vision, only people who wore contact lenses could be tested. The experiment was run on an IBM compatible personal computer with a 20-inch monitor (1024 by 768 resolution, refresh rate 100 Hz) and was programmed using E-prime (Psychology Software Tools Inc., Pittsburgh, PA, USA).