She was treated with an antiplatelet agent and prednisolone to limit platelet activation and destruction. In parallel with clinical amelioration, levels of plasma platelet microparticles (PMPs), a procoagulant
factor in platelet activation, decreased after treatment but increased after learn more reduction of the prednisolone dose, resulting in progression of vascular stenosis. Immunosuppressive therapy with cyclosporine normalized plasma PMP levels, and no additional vascular events occurred during the 3-month follow-up period. Immunosuppressive therapy to decrease plasma PMP levels is warranted after acute ischemic stroke in the context of idiopathic thrombocytopenic purpura.”
“Within this website the Green Analytical Chemistry paradigm, the best alternative for greening the methods of analysis comprises the direct determination of sample composition and/or sample properties without any chemical sample treatment, and, of course, it would be preferable not to have any physical treatment before acquisition of the information desired.
In this review, we evaluate the state of the art in, and available alternatives for, analysis of solids without prior sample treatment, starting from the non-invasive quality control of products or processes through to the use of portable instruments for in situ determinations and the development of methods
based on image analysis. We evaluate the advantages of such methodologies from the viewpoints of both environmental and operator risk. (C) 2012 Elsevier Ltd. All rights reserved.”
“Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is the third most common respiratory condition after asthma and chronic obstructive airway disease affecting approximately 2-4% of the middle-aged population. OSAHS has a hereditary component but owing to difficulties with phenotyping, its genetic basis has been difficult JAK pathway to elucidate. Despite this, limited progress has been made in considering
the genetic basis of the ‘intermediate phenotypes’ of OSAHS such as craniofacial structure and upper airway control. Obesity is a risk factor for the development of OSAHS. The genetics of obesity are complex, but advances have been made recently using genome-wide association studies. Some authors postulate that OSAHS and common obesity share many pathophysiological pathways. However, the genes underpinning the development of sleep-disordered breathing and obesity are likely to be different, despite phenotypes that appear to overlap and influence each other’s expression. This paper focuses on human studies over-viewing the most recent work in the area and includes a brief discussion on methods of genetic studies. Copyright (C) 2009 S. Karger AG, Basel”
“Purpose: To evaluate the effect of a topical application of a cream formulation containing extract of Acacia nilotica bark extract on human cheek skin texture.